About Us
Supertechs was established in 1982 in Rockville, Maryland for the purpose of producing monospecific antibodies to Terminal deoxynucleotidyl Transferase (TdT) and to provide these antibodies commercially. Human TdT is a naturally occurring nuclear protein found at a detectable concentration in prelymphocytes during early biological development. Abnormal or cancerous human hematopoietic cells may express an abnormal concentration of TdT independent of the developmental stage. Overpopulation of TdT positive cells in blood and bone marrow is symptomatic of a disease.
The availability of our immunological reagents specific for TdT determination in blood smear, bone marrow, and cell suspension enables researchers and clinicians to accurately and reliably analyze tissue.
Our website is exclusive to immunological reagents for TdT determination. If you have further questions regarding the availability of TdT enzyme or other related products, then please contact our company by phone or email.
General Info & Policies
Analytical and performance characteristics are not established for FDA Class I Analyte Specific Reagents. We are not liable for any damages caused by improper use of our products. All matters related to specific practical applications are the users’ responsibility.
Terms of payment are net 30 days.
Anti-TdT Reagents and Related Products
Supertechs produces immunoaffinity-purified monoclonal anti-TdT antibodies conjugated with fluorescein isothiocyanate (FITC) and their complementary negative control reagents for flow cytometric analysis.
As control cells for flow cytometry studies – Supertechs manufactures lymphoblastoid REH (TdT⁺) and RA-1 (TdT⁻) cells prepared as a fixed cell suspension with about 50% TdT⁺ cells and 50% TdT⁻.
For slide staining, immunoaffinity-purified polyclonal rabbit antibodies specific to human and bovine TdT as well as FITC labeled goat:anti-rabbit reagents are available. These conjugates are usually used for staining of TdT positive cells in blood or bone marrow smears and in paraffin tissue sections.
Flow Cytometry Results of Mononuclear Cell Fractions from a TdT Positive T-ALL Patient
Courtesy of Elisabeth Paietta, Ph.D., Our Lady of Mercy Cancer Center, Bronx, New York.
TdT Testing — Cat# 8100, FITC:Mouse IgG₁ Negative Control (50 µg/mL)
TdT Testing — Cat# 6600, FITC:Mouse anti-Human TdT-6 (50 µg/mL)
TdT positive bone marrow smear of an ALL Patient
A: Phase Contrast
B: Immunofluorescence staining with Supertechs Cat# 0480, FITC Immunofluorescence Reagents
How to Place an Order
For ordering information, please visit our ordering page here.
Replacements and Returns
A Supertechs product is warrantied to meet the specifications outlined in the certificate of analysis and product description. If a product does not meet the specifications or is found to be defective, we will replace or refund the product upon receipt.
Any errors made by Supertechs, Inc. regarding order filling or damage incurred during transit will be corrected immediately at no expense to the customer.